代表性教學(xué)、科研項目或研究成果（論文、專利專著、教材、成果獲獎）： | 1.近5年的科研課題 1） 國家“十四五”重點研發(fā)計劃子課題，基于臨床大數(shù)據(jù)的極/超早產(chǎn)兒救治-后遺癥防治循證醫(yī)學(xué)研究及質(zhì)控體系建設(shè)，2022YFC2704805，336萬元，2022/12-2025/11 2）首都衛(wèi)生發(fā)展科研專項，危重新生兒臍靜脈置管致門脈血栓危險因素及演變結(jié)局前瞻隊列研究,首發(fā)2022-2-2095, 41.6萬元，2022/1-2024/12 3）北京市自然科學(xué)基金面上項目，HMGB1-RAGE/PI3K致缺氧缺血性腦損傷新生大鼠小膠質(zhì)M1/M2極化失衡的機制研究，7192061，20萬元，2019/1-2022/12 4）北京市醫(yī)院管理中心兒科協(xié)同創(chuàng)新課題，基于轉(zhuǎn)運前危重兒評分及轉(zhuǎn)運后診療結(jié)局的危重新生兒轉(zhuǎn)運標(biāo)準(zhǔn)研究，XTCX201816，40萬元，2019/1-2022/12 5）國家自然科學(xué)基金面上項目，HMGB1調(diào)節(jié)CPEB1-NR2A通路在新生兒缺氧缺血性腦損傷發(fā)病機制中的作用研究，81671505，57萬元，2017/1-2020/12 2. 10篇代表性論著（第一作者或通信作者） 1) Sun Y, Zhu X, Zhu K, Yu J, Cheng L, Hei M*. High-mobility Group Box 1 contributes to Hypoxic-ischemic brain damage by facilitating imbalance of microglial polarization through RAGE-PI3K/Akt pathway in neonatal rats[J]. Int J Med Sci, 2022, 19(14): 2093-2103. Doi: 10.7150/ijms.78641 2) Qu W, Shen Y, Qi Y, Jiang M, Zheng X, Zhang J, Wu D, He W, Geng W, Hei M*. Comparison of four neonatal transport scoring methods in the prediction of mortality risk in full-term, out-born infants: A single-centre retrospective cohort study[J]. Eur J Pediatr, 2022 doi.org/10.1007/s00431-022-04506-8 3) Hei M, Li X, Shi Y, Cao Y, Sun J, Wu H, Jiang S, Ma X, Wang Y, Sun H, Zhang H, Du L, Zhou W, Lee SK, Chen C*, on behalf of the Chinese Neonatal Network (CHNN). The Chinese Neonatal Network: a national protocol for collaborative research and quality improvement in neonatal care[J]. BMJ Open 2022;12:e051175. doi:10.1136/bmjopen-2021-051175 4) Zhu K, Zhu X, Sun S, Yang W, Liu S, Tang Z, Zhang R, Shen T, Hei M*. Inhibition of TLR4 Prevents Hippocampal Hypoxic-ischemic Injury by Regulating Ferroptosis in Neonatal Rats[J]. Experiment Neurol. 2021; 345: 113828 doi: 10.1016 5) Zheng X, Geng W, Li G, Jin F, Liu H, Jia S, Hei M*. Retrieval of an intracardiac cannula fragment via femoral access in a premature infant. Neonatology, 2021 DOI 10.1159/000515464 6) M Hei*, X Gao, Y Li, X Gao, Z Li, S Xia, A Zhang, S Han, H Gao, S Nong, A Zhang, J Li, T Wang, XY Ye, SK Lee. Family integrated care for preterm infants in China: A cluster randomized controlled trail. J Pediatr, 2021, 228:36-43 7) Sun Y, Hei* M, Fang Z, Tang Z, Wang B, Hu N. High-mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia. Front Cell Neurosci. 2019; 13: 506 8) Tang Z, Cheng S, Sun Y, Zhang Y, Xiang X, Ouyang Z, Zhu X, Wang B, Hei M*. Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. Experiment Neurol. 2019; 321: 11309-11322 9) Hei M, Yi Z*. Environmental factors for the development of fetal urinary malformations. World J Pediatrics, 2014;10 (1): 17-23 10) Hei M*, Luo Y, Zhang X, Liu F. Tanshinone IIa Alleviates the Biochemical Changes Associated with Hypoxic Ischemic Brain Damage in a Rat Model. Phytotherapy Research, 2011, 25(12): 1865-1869 3. 專利 1）黑明燕，耿文靜，靳緋，姜敏，董世霄，向希盈. 用于臍靜脈穿刺的擴張器. 實用新型專利，2020年4月21日，ZL2019 2 0799882.0 4. 參編教材 1）陳超，杜立中，封志純主編. 新生兒學(xué)（第1版）. 人民衛(wèi)生出版社，2022年，北京 ISBN 978-7-117-29745-5 2）王天有，申昆玲，沈穎主編. 諸福棠實用兒科學(xué)（第9版）. 人民衛(wèi)生出版社，2022年，北京 ISBN 978-7-117-32904-0 5. 成果獲獎 2021年度首都醫(yī)科大學(xué)科學(xué)技術(shù)獎科技進(jìn)步獎二等獎（排名第1），家庭參與式看護(hù)對危重新生兒的腦保護(hù)與機制，首都醫(yī)科大學(xué) |
